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Tisha King‑Heiden

Pronouns: She/Her/Hers
Professor
Biology University of Wisconsin-La Crosse

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Tisha King‑Heiden Pronouns: She/Her/Hers

Professor

Biology

Specialty area(s)

Reproductive physiology, reproductive toxicology, and developmental toxicology.  

Current courses at UWL

I am on a research sabbatical for Spring 2025.

Education

PhD University of Wisconsin-Milwaukee Great Lakes WATER Institute, 2005

MS University of North Carolina - Greensboro, 1998

BS University of Wisconsin - Stevens Point, 1996

Career

Teaching history

Bio 105 (General Biology)

Bio 260 (Special Topics: Environmental and Health Effects of Water Pollution)

Bio 312 (Human Anatomy & Physiology I)

Bio 313 (Human Anatomy & Physiology II)

Bio 421/521 (Comparative Vertebrate Endocrinology)

Bio 441/541 (Environmental Toxicology)

Bio 718 (Advanced Human Physiology I)

Research and publishing

RESEARCH PUBLICATIONS (*indicates undergraduate student; †graduate student):

J Scheuller†, M Boogaard, C Kirkeeng, N Schloesser, S Wolf†, A Lettenberger*, TC King-Heiden, and J Luoma. 2024. Determination of Larval Sea Lamprey (Petromyzon marinus) Seasonal Sensitivity Differences to Lampricide Treatment. J Great Lakes Research.  https://doi.org/10.1016/j.jglr.2023.102248 

AJ Jeninga†, N Kooij*, E Harrahy, and TC King-Heiden. 2023.  Binary mixtures of imidacloprid and thiamethoxam do not appear to cause additive toxicity in fathead minnow larvae (Pimephales promelas).  “Women in Ecotoxicology” Special Issue. Front. Toxicol. 5:1282817. https://doi:10.3389/ftox.2023.1282817

AJ Jeninga†, Z Wallace*, S Victoria†, E Harrahy, and TC King-Heiden.  2023.  Chronic exposure to environmentally relevant concentrations of imidacloprid impacts survival and ecologically relevant behaviors of fathead minnow larvae. Env. Tox and Chem. 42(10): 2184-2192 DOI: 10.1002/etc.5710 

S Victoria†, M Hein*, E Harrahy and TC King-Heiden.  2022. Potency matters: Impacts of embryonic exposure to nAChR agonists thiamethoxam and nicotine on hatching success, growth, and neurobehavior in larval zebrafish.  J Toxicol Env Health, A.  85(18):767-782.

S Victoria†, S Duffy*, E Harrahy and TC King-Heiden.  2022.  Embryonic exposure to thiamethoxam reduces survival and alters neurobehavior of fathead minnows.  Env. Tox. and Chem.  41(5):1276-1285.

A Stenzel*, H Wirt*, A Patten*, B Theodore*, and TC King-Heiden.  2019.  Larval exposure to environmentally relevant concentrations of triclosan impairs metamorphosis and reproductive fitness in zebrafish.  Repro. Toxicol. 87:79-86.

R Ryan†, C Belby, TC King-Heiden, RJ Haro, J Ogorek†, and G Gerrish.  2019. The role of macroinvertebrate in the distribution of lead (Pb) within a marsh ecosystem. Hydrobiologica. 827:337-352.

H, Wirt*, R Botka*, KE Perez, and TC King-Heiden.  2018.  Embryonic exposure to environmentally relevant concentrations of triclosan impairs foraging efficiency in zebrafish larvae.  Env. Tox. and Chem.  37(12):3124-3133.

AJ Olson*, T Cyphers†, G Gerrish, C Belby, and TC King-Heiden.  2018. Evaluating the toxicity of contaminated sediments from an urban wetland: A case study approach to develop a molecular biomarker for exposure to lead in zebrafish. J Toxicol Environ Health (A). 81(18):924-938.

Q Liu, RH Klingler, B Wimpee, M Dellinger, TC King-Heiden, J Wehr Grzybowski*, SL Gerstenberger, DN Weber, and MJ Carvan, III.  2016.  Maternal methylmercury from a wild-caught walleye diet induces developmental abnormalities in zebrafish. Repro. Toxicol. 65:272-282.

A Saley*, M Hess*, K Miller*, D Howard, and TC King-Heiden.  2016. Cardiac toxicity of triclosan in developing zebrafish.  Zebrafish: Special Issue on Toxicology.  13(5): 399-404.

N Carmosini, S Grandstrand*, and TC King-Heiden. 2016.  Developmental toxicity of triclosan in the presence of dissolved organic carbon: Moving beyond standard acute toxicity assays to understand ecotoxicological risk. Zebrafish: Special Issue on Toxicology.  13(5): 424-431.

Lor*, Y, A Revak*, J Weigand*, E Hicks*, D Howard, and TC King-Heiden.  2015.  Juvenile exposure to vinclozolin shifts sex ratios and impairs reproductive capacity of zebrafish. Repro Tox 58:111-118.

RJ Hutz, M Carvan, III, JK Larson, Q Liu, RV Stelzer, TC King-Heiden, MG Baldridge, N Shahnoor and K Julien.  2014. Familiar and novel reproductive endocrine disruptors: xenoestrogens, dioxins and nanoparticles. Current Trends Endocrinol. 7:111-122.

TR Baker, TC King-Heiden, W Heideman, RE Peterson. 2014. Dioxin induction of transgenerational inheritance of disease in zebrafish. Mol Cell Endocrinol. 398:36-41.  Invited Review.

Chollett*, D, KE Perez, and TC King-Heiden.  2014. Embryonic exposure to sublethal concentrations of 2,3,7,8-TCDD impairs prey capture by zebrafish larvae. Environ. Toxicol. Chem. 33(4): 784-790. Selected by editorial board as one of top 5 exceptional papers in ETC 2014.

Wiecinski, PN, KM Metz, TC King-Heiden, K Lewis, AN Mangham, RJ Hamers, W Heideman, RE Peterson, and JA Pederson. 2013. Toxicity of oxidatively degraded quantum dots. Environ. Sci. and Technol.  47(16):9132-9139.

King-Heiden, TC, V Mehta, KM Xiong, KA Lanham, DS Antkiewicz, A Ganser*, W Heideman, RE Peterson.  2012. Reproductive and developmental toxicity of dioxin in fish. Mol. Cell Endo. 354(1-2):121-38. 

King-Heiden, TC, PN Wiecinski, AN Mangham, KM Metz, D Nesbit, JA Pederson, RJ Hamers, W Heideman, and RE Peterson. 2009. Quantum Dot nanotoxicity assessments using the zebrafish embryo. Environ. Sci. and Technol. 43(5):1605-1611.

King-Heiden, TC, J Spitsbergen, W Heideman, and RE Peterson.  2009.  Persistent adverse effects on health and reproduction caused by exposure of zebrafish to 2,3,7,8-tetrachlorodibenzo-p-dioxin during early development and gonad differentiation. Tox Sci. 109(1):75-87.

Hill, AJ, TC King-Heiden, W Heideman, W, and RE Peterson.  2009.  Roles of ARNT2 in zebrafish embryonic development. Zebrafish. 6(1): 79-91.

King-Heiden, TC, CA Struble, ML Rise, MJ Hessner, RJ Hutz, and MJ Carvan, III. 2008. Molecular targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin within the zebrafish ovary: Insights into TCDD’s ovarian toxicity.  Reprod. Toxicol.  25(1):47-57.

King-Heiden, TC, E Dengler, WJ Gao, W Heideman, and RE Peterson.  2007.  Developmental toxicity of low generation PAMAM dendrimers in Zebrafish.  Toxicol. Appl. Pharm. 225:70-79.

Hutz, RJ, MJ Carvan III, MG Baldridge, LK Conely, and TC King-Heiden.  2006.  Environmental toxicants and effects on female reproductive function, Review. Trends in Repro. Biol. 2:1-11.

King-Heiden, TC, MJ Carvan, III, and RJ Hutz.  2006.  Inhibition of follicular development, vitellogenesis, and 17β estradiol concentrations in zebrafish following chronic, sublethal dietary exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.  Tox. Sci. 90(2): 490-499.

King-Heiden, TC, RJ Hutz, and MJ Carvan, III.  2005.  Accumulation and maternal transfer of TCDD: Effects on reproductive success of female zebrafish. Tox Sci.  87(2):497-507.

King-Heiden, TC, A Neal Haines, C Manire, J Lombardi, and TJ Koob.  2005.  Ultrastructure and permeability of the egg capsule of the bonnethead shark, Sphyrna tiburo. J. Exp. Zool. 303A(7):577-589.

BOOK CHAPTERS:

KE Perez and TC King-Heiden. 2018. Geometric morphometrics as a tool to evaluate teratogenic effects in zebrafish (Danio rerio).  In Teratogenicity Testing: Methods and Protocols.  I  Springer.  Pg. 373-391.

Carvan III, MJ, TC King-Heiden, and H Tomasiawicz.  2005.  The Utility of Zebrafish as a Model for Toxicological Research.  In Biochemistry and Molecular Biology of Fishes, vol 6 Environmental Toxicology.  TP Mommsen and TW Moon, eds.  Elsevier BV. Pp. 3-41.

RESEARCH IN THE AREA OF TEACHING AND LEARNING (SOTL):

TC King-Heiden and ME Litster. 2018. Using learning cycle based modules to promote a better understanding of the evolutionary processes that shape human health. J of Bio Ed, in press.

Gerrish, G, T King-Heiden, A, Sanderfoot, M Abler, K Perez.  2014.  Building the impetus for change: an across curriculum Vision & Change initiative in Biology.  J College Sci Teaching. 44(4):28-35.

Kudos

presented

Tisha King-Heiden, Biology, presented "Minnow Models for Toxicology" at Phenological initiatives for INdigenous Peoples in Limnology (PhIN) on Feb. 7 in the Trout Lake Research Station in Minocqua, WI. The workshop was co-organized by the Lac du Flambeau Tribal Natural Resources Department and the UW Center for Limnology Trout Lake station. She was honored to be invited to participate in this workshop where she learned about Tribal approaches to protecting water quality. The workshop infused Indigenous and traditional foods such as buffalo, milk weed, and fry bread. It also involved making fish decoys used in ice spear-fishing and sharing the origins and use of the games of snow snake and lacrosse.

Submitted on: Feb. 12

published

Tisha King-Heiden, Biology, authored the article "Adaptation of the in vivo respiratory burst assay for fathead minnow larvae (Pimephales promelas)" in the Journal of Immunological Methods and was accepted for publication by elsevier. Nicole Kooij, May 2024 biology graduate, was first author on this technical note publication. Kooij is currently a doctoral student at the Medical College of Wisconsin in immunology.

Submitted on: Dec. 18, 2024

presented

Tisha King-Heiden, Biology, presented "Toxicity testing with small fish models: Bridging gaps between ecotoxicology and human health" at the University of Mississippi Bimolecular Sciences External Scientist Seminar Series on Nov. 7 in Oxford, MS. She also was a guest instructor for Bio Molecular Sciences 601: Graduate Student Survival Strategies, where she provided first-year, doctoral students with tips for successful grant applications.

Submitted on: Nov. 10, 2024

presented

Emily Erickson and Audrey Quackenbush, biology students, and Tisha King-Heiden, professor of Biology, presented "Exploring the potential immunotoxicity of imidacloprid in fathead minnow larvae (Pimephales promelas) " at Midwest Society of Environmental Toxicology and Chemistry annual meeting on April 11 in La Crosse, WI.

Submitted on: April 17, 2024

presented

Tisha King-Heiden, Biology; and Cheyenne Bennett and Anders Cedergren, both Public Health & Community Health Education students; presented "Gauging UWL Student Awareness of PFAS Contamination in Wisconsin " at Midwest Society of Environmental Toxicology and Chemistry annual meeting on April 11 in La Crosse, WI.

Submitted on: April 17, 2024

Memberships & affiliations

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